Botulinum Neurotoxins: 2157 (Current Topics in Microbiology - download pdf or read online

By Andreas Rummel,Thomas Binz

ISBN-10: 3642335691

ISBN-13: 9783642335693

ISBN-10: 3642448895

ISBN-13: 9783642448898

The super powerful substance botulinum neurotoxin (BoNT) has attracted a lot curiosity in varied fields. initially pointed out as reason for the infrequent yet lethal illness botulism, army and terrorist meant to misuse this subtle molecule as organic weapon. This triggered its category as opt for agent classification A through the facilities for ailments regulate and Prevention and the directory within the organic and Toxin guns conference. Later, the civilian use of BoNT as lengthy performing peripheral muscle relaxant has became this molecule into an vital pharmaceutical around the world with annual sales >$1.5 billion. additionally easy scientists price the botulinum neurotoxin as molecular device for dissecting mechanisms of exocytosis. This publication will disguise the newest molecular info of botulinum neurotoxin, its mechanism of motion in addition to its detection and application.

Show description

Read Online or Download Botulinum Neurotoxins: 2157 (Current Topics in Microbiology and Immunology) PDF

Similar pharmacology books

Receptor - Based Drug Design: 89 by Paul Leff PDF

Applying quite a lot of examples from G-protein-coupled receptors and ligand-gated ion channels, this special, single-source reference illustrates the rules of pharmacological research and receptor type which are the foundation of rational drug layout. Explains the experimental and theoretical tools used to symbolize interactions among ligands and receptors-providing the pharmacological details had to remedy therapy difficulties and facilitate the drug layout strategy!

Download PDF by Joseph Ragaz,Pierre R. Band,James H. Goldie: Preoperative (Neoadjuvant) Chemotherapy (Recent Results in

Regardless of fresh advances in adjuvant remedies of melanoma, the regi­ mens of postoperative adjuvant chemotherapy therapy that are almost immediately to be had fail to therapy the vast majority of melanoma sufferers. Pre­ operative (neoadjuvant) chemotherapy represents a brand new procedure in drug scheduling, in line with sound theoretical, pharmacokinetic, and experimental ideas.

Mark C. Rogge,David R. Taft's Preclinical Drug Development (Drugs and the Pharmaceutical PDF

This reference discusses intimately the vast realm of preclinical drug improvement. themes diversity from overview of pharmacology and toxicology throughout the regulatory expectancies that help medical trials. offering chapters on pharmacokinetics, modeling and simulation, formula and routes of management, toxicity reviews, the evaluation of drug absorption and metabolism, and interspecies scaling, this advisor is a basic source for medicinal chemists, biologists, and different experts within the drug improvement sciences.

Download e-book for kindle: Advances in Drug Research: 21 by Bernard Testa

Advances in Drug examine, quantity 21 contains 3 chapters that take care of the final topic, particular healing category, and chemical family members of various medications. the 1st bankruptcy of this ebook discusses the absorption and distribution of gear within the lymphatic approach. A presentation of the anti-infective quinolones is supplied in bankruptcy 2, whereas the layout and healing power of peptides are elaborated in bankruptcy three.

Extra resources for Botulinum Neurotoxins: 2157 (Current Topics in Microbiology and Immunology)

Example text

Download PDF sample

Botulinum Neurotoxins: 2157 (Current Topics in Microbiology and Immunology) by Andreas Rummel,Thomas Binz

by Kevin

Rated 4.37 of 5 – based on 20 votes