Chemokine Receptors as Drug Targets, Volume 46 (Methods and by Martine J. Smit,Sergio A. Lira,Rob Leurs PDF

By Martine J. Smit,Sergio A. Lira,Rob Leurs

ISBN-10: 3527321187

ISBN-13: 9783527321186

Chemokines are hormone-like signaling molecules secreted through cells to sign an infection and consultant the immune reaction. Following a decade of simple chemokine examine, the pharmaceutical has now began to take advantage of this important signaling pathway for the advance of leading edge medications opposed to AIDS, melanoma, neural and autoimmune illnesses. here's the 1st reference targeting those novel drug improvement opportunities.
starting with a normal creation on chemokine functionality and chemokine receptor biology, the second one half covers the identified implications of those signaling molecules in human illnesses, akin to melanoma, neural issues, and viral an infection, together with AIDS. The 3rd half systematically surveys present drug improvement efforts at concentrating on person chemokine receptors, in addition to different chemokine interplay companions, together with updated experiences from the pharmaceutical industry.

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Chemokine Receptors as Drug Targets, Volume 46 (Methods and Principles in Medicinal Chemistry) by Martine J. Smit,Sergio A. Lira,Rob Leurs

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